Citalopram attenuated neurobehavioral, biochemical, and metabolic alterations in transient middle cerebral artery occlusion model of stroke in male Wistar rats.

Gupta, Sangeetha; Upadhayay, Deepti; Sharma, Uma; Jagannathan, Naranamangalam R; Gupta, Yogendra Kumar

Gupta, Sangeetha; Upadhayay, Deepti; Sharma, Uma; Jagannathan, Naranamangalam R; Gupta, Yogendra Kumar.

Afiliação

Gupta S; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi-110029, India.
Upadhayay D; Department of NMR & MRI Facility, All India Institute of Medical Sciences, New Delhi-110029, India.
Sharma U; Department of NMR & MRI Facility, All India Institute of Medical Sciences, New Delhi-110029, India.
Jagannathan NR; Department of NMR & MRI Facility, All India Institute of Medical Sciences, New Delhi-110029, India.
Gupta YK; Department of Pharmacology, All India Institute of Medical Sciences, New Delhi-110029, India.

J Neurosci Res ; 96(7): 1277-1293, 2018 07.

Article em En | MEDLINE | ID: mdl-29656429

Assuntos

Isquemia Encefálica/tratamento farmacológico; Citalopram/farmacologia; Infarto da Artéria Cerebral Média/tratamento farmacológico; Acidente Vascular Cerebral/tratamento farmacológico; Animais; Encéfalo/metabolismo; Isquemia Encefálica/metabolismo; Glutationa/metabolismo; Masculino; Malondialdeído/metabolismo; Fármacos Neuroprotetores/farmacologia; Estresse Oxidativo/efeitos dos fármacos; Ratos; Ratos Wistar; Teste de Desempenho do Rota-Rod; Acidente Vascular Cerebral/metabolismo

Palavras-chave

MCAo; apoptosis; citalopram; graphpad prism RRID: SCR_002798; neuroinflammation; neurometabolites; oxidative stress; paravision RRID: SCR_001964; proton nuclear magnetic resonance spectroscopy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citalopram / Isquemia Encefálica / Acidente Vascular Cerebral / Infarto da Artéria Cerebral Média Tipo de estudo: Guideline / Prognostic_studies Limite: Animals Idioma: En Revista: J Neurosci Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia

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