End-tidal CO2-guided automated robot CPR system in the pig. Preliminary communication.
Resuscitation
; 127: 119-124, 2018 06.
Article
em En
| MEDLINE
| ID: mdl-29665427
ABSTRACT
BACKGROUND:
Our aim was to compare the efficacy of the end-tidal CO2-guided automated robot CPR (robot CPR) system with manual CPR and mechanical device CPR.METHODS:
We developed the algorithm of the robot CPR system which automatically finds the optimal compression position under the guidance of end-tidal CO2 feedback in swine models of cardiac arrest. Then, 18 pigs after 11â¯min of cardiac arrest were randomly assigned to one of three groups, robot CPR, LUCAS CPR, and manual CPR groups (nâ¯=â¯6 each group). Return of spontaneous circulation (ROSC) and Neurological Deficit Score 48â¯h after ROSC were compared.RESULTS:
A ROSC was achieved in 5 pigs, 4 pigs, and 3 pigs in the robot CPR, LUCAS CPR, and manual CPR groups, respectively (pâ¯=â¯0.47). Robot CPR showed a significant difference in Neurological Deficit Score 48â¯h after ROSC compared to manual CPR, whereas LUCAS CPR showed no significant difference over manual CPR. (pâ¯=â¯0.01; Robot versus Manual adjusted pâ¯=â¯0.04, Robot versus LUCAS adjusted pâ¯=â¯0.07, Manual versus LUCAS adjusted pâ¯=â¯1.00).CONCLUSIONS:
The end-tidal CO2-guided automated robot CPR system did not significantly improve ROSC rate in a swine model of cardiac arrest. However, robot CPR showed significant improvement of Neurological Deficit Score 48â¯h after ROSC compared to Manual CPR while LUCAS CPR showed no significant improvement compared to Manual CPR.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Reanimação Cardiopulmonar
/
Parada Cardíaca
/
Massagem Cardíaca
Tipo de estudo:
Clinical_trials
/
Evaluation_studies
/
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Resuscitation
Ano de publicação:
2018
Tipo de documento:
Article