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Ondansetron blocks wild-type and p.F503L variant small-conductance Ca2+-activated K+ channels.
Ko, Jum-Suk; Guo, Shuai; Hassel, Jonathan; Celestino-Soper, Patricia; Lynnes, Ty C; Tisdale, James E; Zheng, James J; Taylor, Stanley E; Foroud, Tatiana; Murray, Michael D; Kovacs, Richard J; Li, Xiaochun; Lin, Shien-Fong; Chen, Zhenhui; Vatta, Matteo; Chen, Peng-Sheng; Rubart, Michael.
Afiliação
  • Ko JS; The Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Guo S; Wonkwang University School of Medicine and Hospital, Iksan, South Korea.
  • Hassel J; The Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Celestino-Soper P; The Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Lynnes TC; Department of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana.
  • Tisdale JE; Department of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana.
  • Zheng JJ; Department of Pharmacy Practice, College of Pharmacy, Purdue University , West Lafayette, Indiana.
  • Taylor SE; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Foroud T; Regenstrief Institute , Indianapolis, Indiana.
  • Murray MD; Department of Biostatistics, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Kovacs RJ; Department of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana.
  • Li X; Department of Pharmacy Practice, College of Pharmacy, Purdue University , West Lafayette, Indiana.
  • Lin SF; Regenstrief Institute , Indianapolis, Indiana.
  • Chen Z; The Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Vatta M; Department of Biostatistics, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Chen PS; The Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University School of Medicine , Indianapolis, Indiana.
  • Rubart M; Institute of Biomedical Engineering, National Chiao-Tung University, Hsin-Chu, Taiwan.
Am J Physiol Heart Circ Physiol ; 315(2): H375-H388, 2018 08 01.
Article em En | MEDLINE | ID: mdl-29677462

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do QT Longo / Ondansetron / Bloqueadores dos Canais de Potássio / Canais de Potássio Ativados por Cálcio de Condutância Baixa / Antiarrítmicos Limite: Animals / Female / Humans / Middle aged Idioma: En Revista: Am J Physiol Heart Circ Physiol Assunto da revista: CARDIOLOGIA / FISIOLOGIA Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do QT Longo / Ondansetron / Bloqueadores dos Canais de Potássio / Canais de Potássio Ativados por Cálcio de Condutância Baixa / Antiarrítmicos Limite: Animals / Female / Humans / Middle aged Idioma: En Revista: Am J Physiol Heart Circ Physiol Assunto da revista: CARDIOLOGIA / FISIOLOGIA Ano de publicação: 2018 Tipo de documento: Article