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Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Yoshizawa, Takuya; Ali, Rustam; Jiou, Jenny; Fung, Ho Yee Joyce; Burke, Kathleen A; Kim, Seung Joong; Lin, Yuan; Peeples, William B; Saltzberg, Daniel; Soniat, Michael; Baumhardt, Jordan M; Oldenbourg, Rudolf; Sali, Andrej; Fawzi, Nicolas L; Rosen, Michael K; Chook, Yuh Min.
Afiliação
  • Yoshizawa T; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Ali R; Department of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Jiou J; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Fung HYJ; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Burke KA; Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA.
  • Kim SJ; Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Lin Y; Department of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute (HHMI) Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
  • Peeples WB; Department of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute (HHMI) Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
  • Saltzberg D; Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Soniat M; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Baumhardt JM; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Oldenbourg R; Marine Biological Laboratories, 7 MBL Street, Woods Hole, MA 02543, USA.
  • Sali A; Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Fawzi NL; Department of Molecular Pharmacology, Physiology and Biotechnology, Brown University, Providence, RI 02912, USA.
  • Rosen MK; Department of Biophysics and Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute (HHMI) Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543, USA. Electronic address: michael.rosen@utsouthwestern.edu
  • Chook YM; Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute (HHMI) Summer Institute, Marine Biological Laboratory, Woods Hole, MA 02543, USA. Electronic address: yuhmin.chook@utsouthwestern.edu.
Cell ; 173(3): 693-705.e22, 2018 04 19.
Article em En | MEDLINE | ID: mdl-29677513
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sinais de Localização Nuclear / Transporte Ativo do Núcleo Celular / Beta Carioferinas / Proteína FUS de Ligação a RNA Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sinais de Localização Nuclear / Transporte Ativo do Núcleo Celular / Beta Carioferinas / Proteína FUS de Ligação a RNA Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos