CRISPR genetic screens to discover host-virus interactions.
Curr Opin Virol
; 29: 87-100, 2018 04.
Article
em En
| MEDLINE
| ID: mdl-29684735
ABSTRACT
Viruses impose an immense burden on human health. With the goal of treating and preventing viral infections, researchers have carried out genetic screens to improve our understanding of viral dependencies and identify potential anti-viral strategies. The emergence of CRISPR genetic screening tools has facilitated this effort by enabling host-virus screens to be undertaken in a more versatile and fidelitous manner than previously possible. Here we review the growing number of CRISPR screens which continue to increase our understanding of host-virus interactions.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vírus
/
Viroses
/
Testes Genéticos
/
Interações Hospedeiro-Patógeno
/
Sistemas CRISPR-Cas
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Curr Opin Virol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos