BRAF inhibition with concomitant tumor treating fields for a multiply progressive pleomorphic xanthoastrocytoma.
CNS Oncol
; 7(2): CNS10, 2018 04.
Article
em En
| MEDLINE
| ID: mdl-29708404
ABSTRACT
Pleomorphic xanthoastrocytomas can be very resistant to treatment if they progress after standard therapy with surgery and radiation. We present the case of a patient with a multiply recurrent pleomorphic xanthoastrocytoma which demonstrated a sustained partial response to a combination regimen of the BRAF inhibitor vemurafenib and tumor treating fields. The regimen proved tolerable and efficacious in this case.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Astrocitoma
/
Neoplasias Encefálicas
/
Terapia por Estimulação Elétrica
/
Proteínas Proto-Oncogênicas B-raf
/
Inibidores de Proteínas Quinases
/
Vemurafenib
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
CNS Oncol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos