The acceptability, feasibility, and possible benefits of a neurobiologically-informed 5-day multifamily treatment for adults with anorexia nervosa.
Int J Eat Disord
; 51(8): 863-869, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-29722047
ABSTRACT
OBJECTIVE:
Novel treatments for adults with anorexia nervosa (AN) are lacking. Recent scientific advances have identified neurobiologically-driven temperament contributors to AN symptoms that may guide development of more effective treatments. This preliminary study evaluates the acceptability, feasibility and possible benefits of a multicenter open trial of an intensive 5-day neurobiologically-informed multifamily treatment for adults with AN and their supports (SU). The temperament-focused treatment combines psychoeducation of AN neurobiology and SU involvement to develop skills to manage traits contributing to disease chronicity.METHOD:
Fifty-four adults with AN and at least one SU (n = 73) received the 5-day treatment. Acceptability, feasibility, and attrition were measured post-treatment. Clinical outcome (BMI, eating disorder psychopathology, family function) was assessed post-treatment and at >3-month follow-up.RESULTS:
The treatment had low attrition, with only one drop-out. Patients and SU rated the intervention as highly acceptable, and clinicians reported good feasibility. At post-treatment, patients demonstrated significantly increased BMI, reduced eating disorder psychopathology, and improved family function. Benefits were maintained in the 39 patients who completed follow-up assessment, with 62% reporting full or partial remission.DISCUSSION:
Preliminary results are promising and suggest this novel treatment is feasible and acceptable. To establish treatment efficacy, fully-powered randomized controlled trials are necessary.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Neurobiologia
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Anorexia Nervosa
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Resultado do Tratamento
Tipo de estudo:
Clinical_trials
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Qualitative_research
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Int J Eat Disord
Ano de publicação:
2018
Tipo de documento:
Article