[Effects of different medications with tadalafil on erectile dysfunction in males with primary sexual failure].
Zhonghua Nan Ke Xue
; 23(6): 522-526, 2017 Jun.
Article
em Zh
| MEDLINE
| ID: mdl-29722944
ABSTRACT
OBJECTIVE:
To evaluate the effects of three different medications with tadalafil on erectile dysfunction (ED) in young men with primary sexual failure.METHODS:
This study included 76 male ED patients aged 21ï¼35 years who had primary sexual failure but normal nocturnal penile tumescence and rigidity and failed to respond to psychotherapy. We randomly assigned them to receive oral tadalafil once daily, on demand, or once-daily + on-demand. After 2ï¼3 months of treatment, we evaluated the effects based on the scores of the patients in the five domains of the International Index of Erectile Function (IIEF-5).RESULTS:
After medication, all the patients showed significantly increased scores in the four domains of IIEF-5, namely, erectile function, orgasmic function, intercourse satisfaction, and overall satisfaction. The on-demand group achieved even higher scores in erectile and orgasmic functions but a lower score in sexual desire than the once-daily group. However, the patients in the once-daily + on-demand group exhibited more significant improvement than those in the other two in all the five domains.CONCLUSIONS:
Once-daily + on-demand medication with tadalafil can significantly enhance the therapeutic effect on psychogenic ED in young men with primary sexual failure.Palavras-chave
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Vasodilatadores
/
Agentes Urológicos
/
Tadalafila
/
Disfunção Erétil
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Humans
/
Male
Idioma:
Zh
Revista:
Zhonghua Nan Ke Xue
Assunto da revista:
MEDICINA REPRODUTIVA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China