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Development and validation of a highly sensitive LC-MS/MS method for determination of brain active agent dianhydrogalactitol in mouse plasma and tissues: Application to a pharmacokinetic study.
Sun, Lihan; Wu, Huajing; Ren, Lianjie; Cong, Jiaojiao; Qin, Xiaohui; Wang, Xingli; Qi, Xinming; Kang, Lifeng; Zhang, Junying; Wu, Chunyong.
Afiliação
  • Sun L; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China.
  • Wu H; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Ren L; Center for Drug Evaluation, China Food and Drug Administration, Beijing 100038, China.
  • Cong J; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China.
  • Qin X; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China.
  • Wang X; Department of TCMs Pharmaceuticals, China Pharmaceutical University, Nanjing 210009, China.
  • Qi X; Center for Drug Safety Evaluation and Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Kang L; Faculty of Pharmacy, University of Sydney, NSW 2006, Australia.
  • Zhang J; Department of TCMs Pharmaceuticals, China Pharmaceutical University, Nanjing 210009, China. Electronic address: ivy366300@hotmail.com.
  • Wu C; Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing 210009, China; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China. Electronic address: cywu@cpu.edu.cn.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1087-1088: 90-97, 2018 Jun 15.
Article em En | MEDLINE | ID: mdl-29730531
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatografia Líquida / Dianidrogalactitol / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromatografia Líquida / Dianidrogalactitol / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China