Impact of Drug Interactions on Clobazam and N-Desmethylclobazam Concentrations in Pediatric Patients With Epilepsy.

Russell, Gabrielle R; Phelps, Stephanie J; Shelton, Chasity M; Wheless, James W

Russell, Gabrielle R; Phelps, Stephanie J; Shelton, Chasity M; Wheless, James W.

Afiliação

Russell GR; Department of Clinical Pharmacy and Translational Science, The University of Tennessee Health Science Center, Memphis, Tennessee.
Phelps SJ; Le Bonheur Children's Hospital, Memphis, Tennessee.
Shelton CM; Department of Clinical Pharmacy and Translational Science, The University of Tennessee Health Science Center, Memphis, Tennessee.
Wheless JW; Department of Clinical Pharmacy and Translational Science, The University of Tennessee Health Science Center, Memphis, Tennessee.

Ther Drug Monit ; 40(4): 452-462, 2018 08.

Article em En | MEDLINE | ID: mdl-29746397

Assuntos

Benzodiazepinas/sangue; Clobazam/sangue; Clobazam/farmacocinética; Inibidores do Citocromo P-450 CYP2C19/farmacologia; Indutores do Citocromo P-450 CYP3A/farmacologia; Epilepsia/sangue; Adolescente; Adulto; Fatores Etários; Anticonvulsivantes/farmacocinética; Criança; Pré-Escolar; Interações Medicamentosas; Feminino; Humanos; Lactente; Masculino; Estudos Retrospectivos; Adulto Jovem

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Epilepsia / Indutores do Citocromo P-450 CYP3A / Inibidores do Citocromo P-450 CYP2C19 / Clobazam Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: Ther Drug Monit Ano de publicação: 2018 Tipo de documento: Article

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