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Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes.
Saiki, Julie P; Cao, Hongbin; Van Wassenhove, Lauren D; Viswanathan, Vignesh; Bloomstein, Joshua; Nambiar, Dhanya K; Mattingly, Aaron J; Jiang, Dadi; Chen, Che-Hong; Stevens, Matthew C; Simmons, Amanda L; Park, Hyun Shin; von Eyben, Rie; Kool, Eric T; Sirjani, Davud; Knox, Sarah M; Le, Quynh Thu; Mochly-Rosen, Daria.
Afiliação
  • Saiki JP; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305.
  • Cao H; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305.
  • Van Wassenhove LD; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305.
  • Viswanathan V; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305.
  • Bloomstein J; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305.
  • Nambiar DK; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305.
  • Mattingly AJ; Department of Cell and Tissue Biology, University of California San Francisco, CA 94143.
  • Jiang D; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305.
  • Chen CH; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305.
  • Stevens MC; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305.
  • Simmons AL; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305.
  • Park HS; Department of Chemistry, Stanford University, Stanford, CA 94305.
  • von Eyben R; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305.
  • Kool ET; Department of Chemistry, Stanford University, Stanford, CA 94305.
  • Sirjani D; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA 94305.
  • Knox SM; Department of Cell and Tissue Biology, University of California San Francisco, CA 94143.
  • Le QT; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305; qle@stanford.edu mochly@stanford.edu.
  • Mochly-Rosen D; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305; qle@stanford.edu mochly@stanford.edu.
Proc Natl Acad Sci U S A ; 115(24): 6279-6284, 2018 06 12.
Article em En | MEDLINE | ID: mdl-29794221
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radioterapia / Glândulas Salivares / Terpenos / Xerostomia / Aldeído Desidrogenase / Aldeídos / Cicloexenos Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Radioterapia / Glândulas Salivares / Terpenos / Xerostomia / Aldeído Desidrogenase / Aldeídos / Cicloexenos Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article