Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma.

Li, Shuai; Fu, Lanyan; Tian, Tian; Deng, Liwen; Li, Huangbin; Xia, Weixiong; Gong, Qing

Li, Shuai; Fu, Lanyan; Tian, Tian; Deng, Liwen; Li, Huangbin; Xia, Weixiong; Gong, Qing.

Afiliação

Li S; Department of Biochemistry and Molecular Biology, GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, 510182, People's Republic of China.
Fu L; Department of Biochemistry and Molecular Biology, GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, 510182, People's Republic of China.
Tian T; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People's Republic of China.
Deng L; Department of Biochemistry and Molecular Biology, GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, 510182, People's Republic of China.
Li H; Department of Biochemistry and Molecular Biology, GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, 510182, People's Republic of China.
Xia W; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People's Republic of China. weixiong32@163.com.
Gong Q; Department of Biochemistry and Molecular Biology, GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, 510182, People's Republic of China. 247945248@qq.com.

Cell Commun Signal ; 16(1): 28, 2018 06 11.

Article em En | MEDLINE | ID: mdl-29891006

Assuntos

Metabolismo dos Lipídeos; Carcinoma Nasofaríngeo/patologia; Superóxido Dismutase-1/metabolismo; Animais; Apoptose; Carnitina O-Palmitoiltransferase/metabolismo; Linhagem Celular Tumoral; Proliferação de Células; Transformação Celular Neoplásica; Feminino; Técnicas de Silenciamento de Genes; Humanos; Estimativa de Kaplan-Meier; Camundongos; Carcinoma Nasofaríngeo/diagnóstico; Carcinoma Nasofaríngeo/genética; Carcinoma Nasofaríngeo/metabolismo; Prognóstico; Espécies Reativas de Oxigênio/metabolismo; Superóxido Dismutase-1/deficiência; Superóxido Dismutase-1/genética

Palavras-chave

CPT1A; Nasopharyngeal carcinoma; ROS; SOD1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metabolismo dos Lipídeos / Superóxido Dismutase-1 / Carcinoma Nasofaríngeo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cell Commun Signal Ano de publicação: 2018 Tipo de documento: Article

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