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High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis.
Mason, Derek M; Weber, Cédric R; Parola, Cristina; Meng, Simon M; Greiff, Victor; Kelton, William J; Reddy, Sai T.
Afiliação
  • Mason DM; Department of Biosystems Science and Engineering, ETH Zürich, Basel 4058, Switzerland.
  • Weber CR; Department of Biosystems Science and Engineering, ETH Zürich, Basel 4058, Switzerland.
  • Parola C; Department of Biosystems Science and Engineering, ETH Zürich, Basel 4058, Switzerland.
  • Meng SM; Life Science Graduate School, Systems Biology, ETH Zürich, University of Zurich, Zurich 8057, Switzerland.
  • Greiff V; Department of Biosystems Science and Engineering, ETH Zürich, Basel 4058, Switzerland.
  • Kelton WJ; Department of Biosystems Science and Engineering, ETH Zürich, Basel 4058, Switzerland.
  • Reddy ST; Department of Biosystems Science and Engineering, ETH Zürich, Basel 4058, Switzerland.
Nucleic Acids Res ; 46(14): 7436-7449, 2018 08 21.
Article em En | MEDLINE | ID: mdl-29931269

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia de Proteínas / Mutagênese Sítio-Dirigida / Sistemas CRISPR-Cas / Anticorpos Limite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Engenharia de Proteínas / Mutagênese Sítio-Dirigida / Sistemas CRISPR-Cas / Anticorpos Limite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça