Interference with KCTD9 inhibits NK cell activation and ameliorates fulminant liver failure in mice.

Zhang, Xiaoping; Zhu, Lin; Zhou, Yaoyong; Shi, Aichao; Wang, Hongwu; Han, Meifang; Wan, Xiaoyang; Kilonzo, Semvua Bukheti; Luo, Xiaoping; Chen, Tao; Ning, Qin

Zhang, Xiaoping; Zhu, Lin; Zhou, Yaoyong; Shi, Aichao; Wang, Hongwu; Han, Meifang; Wan, Xiaoyang; Kilonzo, Semvua Bukheti; Luo, Xiaoping; Chen, Tao; Ning, Qin.

Afiliação

Zhang X; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.
Zhu L; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.
Zhou Y; Department of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shi A; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.
Wang H; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.
Han M; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.
Wan X; Department of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Kilonzo SB; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.
Luo X; Department of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen T; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.
Ning Q; Institute of Infectious Disease, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, # 1095 Jiefang Avenue, Wuhan, 430030, People's Republic of China.

BMC Immunol ; 19(1): 20, 2018 06 25.

Article em En | MEDLINE | ID: mdl-29940856

Assuntos

Células Matadoras Naturais/imunologia; Falência Hepática Aguda/imunologia; Fígado/imunologia; Ativação Linfocitária/imunologia; Canais de Potássio/imunologia; Interferência de RNA; Animais; Células CHO; Sobrevivência Celular/imunologia; Cricetinae; Cricetulus; Vírus da Hepatite B/imunologia; Vírus da Hepatite B/fisiologia; Hepatite B Crônica/imunologia; Hepatite B Crônica/metabolismo; Hepatite B Crônica/virologia; Células Matadoras Naturais/metabolismo; Células Matadoras Naturais/virologia; Fígado/metabolismo; Fígado/virologia; Falência Hepática Aguda/genética; Falência Hepática Aguda/metabolismo; Camundongos Endogâmicos BALB C; Canais de Potássio/genética; Canais de Potássio/metabolismo

Palavras-chave

KCTD9; Liver failure; MHV-3; NK cell; Short hairpin RNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Ativação Linfocitária / Canais de Potássio / Falência Hepática Aguda / Interferência de RNA / Fígado Limite: Animals Idioma: En Revista: BMC Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2018 Tipo de documento: Article

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