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N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation.
Bowie, Laura E; Maiuri, Tamara; Alpaugh, Melanie; Gabriel, Michelle; Arbez, Nicolas; Galleguillos, Danny; Hung, Claudia L K; Patel, Shreya; Xia, Jianrun; Hertz, Nicholas T; Ross, Christopher A; Litchfield, David W; Sipione, Simonetta; Truant, Ray.
Afiliação
  • Bowie LE; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Maiuri T; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Alpaugh M; Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Gabriel M; Department of Biochemistry, Western University, London, ON N6A 3K7, Canada.
  • Arbez N; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore MD 21205.
  • Galleguillos D; Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Hung CLK; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Patel S; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Xia J; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada.
  • Hertz NT; Mitokinin, LLC, New York, NY 10006.
  • Ross CA; Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore MD 21205.
  • Litchfield DW; Department of Biochemistry, Western University, London, ON N6A 3K7, Canada.
  • Sipione S; Department of Pharmacology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
  • Truant R; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada; truantr@mcmaster.ca.
Proc Natl Acad Sci U S A ; 115(30): E7081-E7090, 2018 07 24.
Article em En | MEDLINE | ID: mdl-29987005
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Adenina / Transdução de Sinais / Doença de Huntington / Adutos de DNA / Neurônios Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Adenina / Transdução de Sinais / Doença de Huntington / Adutos de DNA / Neurônios Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá