[Factitious hypoglycemia : "a never-ending story"?] / Hypoglycémie factice : quand l'histoire se répète.
Ann Biol Clin (Paris)
; 76(4): 439-444, 2018 08 01.
Article
em Fr
| MEDLINE
| ID: mdl-29991462
ABSTRACT
Our team of diabetologist is challenged by the case of a 41 year-old woman with recurrent hypoglycaemic episodes. Her clinical background was complex with, among others, a neuroendocrine tumor, a nonalcoholic steatohepatitis and an adrenal insufficiency; these conditions require the exploration of several potential causes. After excluding an endogenous etiology, a factitious hypoglycemia was quicky suspected by clinicians. However, several venous samples showed normal insulinemia and a moderately decreased C-peptide. After multidisciplinary team discussion and facing a strong clinical suspicion, samples were sent to another laboratory to confirm the insulin results. Substantially supratherapeutics insulin concentrations were highlighted. This confirms the previous suspicion of surreptitious insulin administration with a recombinant form unrecognized by our routinely used analyzer. This observation leads us to briefly discuss the lack of cross-reactivities observed with many different insulin assays.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transtornos Autoinduzidos
/
Hipoglicemia
/
Insulina
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Female
/
Humans
Idioma:
Fr
Revista:
Ann Biol Clin (Paris)
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Bélgica