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Two new tetracyclic triterpenoids from the endophytic fungus Hypoxylon sp. 6269.
Liang, Han-Qiao; Zhang, Da-Wei; Guo, Shun-Xing; Yu, Jie.
Afiliação
  • Liang HQ; a The Key Laboratory of Bioactive Substance and Resource Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100193 , China.
  • Zhang DW; b Dean of Biomedical School , Beijing City University , Beijing 100094 , China.
  • Guo SX; a The Key Laboratory of Bioactive Substance and Resource Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development , Chinese Academy of Medical Sciences & Peking Union Medical College , Beijing 100193 , China.
  • Yu J; c Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering , Jiangsu University of Technology , Changzhou 213001 , China.
J Asian Nat Prod Res ; 20(10): 951-956, 2018 Oct.
Article em En | MEDLINE | ID: mdl-30001634
ABSTRACT
Two new tetracyclic triterpenoids, integracide E (1) and isointegracide E (2), as well as three known secondary metabolites (i.e. integracide A (3), 2-deoxyintegracide A (4) and 2-deoxyintegracide B (5)), were isolated from mycelium of the endophytic fungus Hypoxylon sp. 6269. Structures were determined by a combination of 1D and 2D NMR techniques and mass spectrometry. All of the compounds were tested for their anti-HIV-1 integrase activities.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xylariales / Triterpenos / Endófitos Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xylariales / Triterpenos / Endófitos Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China