Liver Glutamate Dehydrogenase Controls Whole-Body Energy Partitioning Through Amino Acid-Derived Gluconeogenesis and Ammonia Homeostasis.

Karaca, Melis; Martin-Levilain, Juliette; Grimaldi, Mariagrazia; Li, Lingzi; Dizin, Eva; Emre, Yalin; Maechler, Pierre

Karaca, Melis; Martin-Levilain, Juliette; Grimaldi, Mariagrazia; Li, Lingzi; Dizin, Eva; Emre, Yalin; Maechler, Pierre.

Afiliação

Karaca M; Department of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland meliskaraca@gmail.com pierre.maechler@unige.ch.
Martin-Levilain J; Faculty Diabetes Center, University of Geneva Medical School, Geneva, Switzerland.
Grimaldi M; Department of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland.
Li L; Faculty Diabetes Center, University of Geneva Medical School, Geneva, Switzerland.
Dizin E; Department of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland.
Emre Y; Faculty Diabetes Center, University of Geneva Medical School, Geneva, Switzerland.
Maechler P; Department of Cell Physiology and Metabolism, University of Geneva Medical School, Geneva, Switzerland.

Diabetes ; 67(10): 1949-1961, 2018 10.

Article em En | MEDLINE | ID: mdl-30002133

Assuntos

Amônia/metabolismo; Gluconeogênese/fisiologia; Glutamato Desidrogenase/metabolismo; Fígado/metabolismo; Animais; Feminino; Gluconeogênese/genética; Homeostase/genética; Homeostase/fisiologia; Metabolismo dos Lipídeos/genética; Metabolismo dos Lipídeos/fisiologia; Fígado/enzimologia; Masculino; Camundongos; Camundongos Knockout; Camundongos Mutantes; Receptores de Glutamato/genética; Receptores de Glutamato/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gluconeogênese / Glutamato Desidrogenase / Amônia / Fígado Limite: Animals Idioma: En Revista: Diabetes Ano de publicação: 2018 Tipo de documento: Article

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