PEGylated self-assembled enzyme-responsive nanoparticles for effective targeted therapy against lung tumors.

Guo, Fangyuan; Wu, Jiangqing; Wu, Wenchao; Huang, Dongxue; Yan, Qinying; Yang, Qingliang; Gao, Ying; Yang, Gensheng

Guo, Fangyuan; Wu, Jiangqing; Wu, Wenchao; Huang, Dongxue; Yan, Qinying; Yang, Qingliang; Gao, Ying; Yang, Gensheng.

Afiliação

Guo F; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China.
Wu J; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China.
Wu W; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China.
Huang D; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China.
Yan Q; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China.
Yang Q; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China.
Gao Y; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China.
Yang G; College of Pharmaceutical Science, Zhejiang University of Technology, #18 Chaowang Road, Hangzhou, 310032, People's Republic of China. yanggs@zjut.edu.cn.

J Nanobiotechnology ; 16(1): 57, 2018 Jul 16.

Article em En | MEDLINE | ID: mdl-30012166

Assuntos

Antineoplásicos/química; Neoplasias Pulmonares/tratamento farmacológico; Metaloproteinases da Matriz/metabolismo; Nanopartículas/química; Animais; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico; Disponibilidade Biológica; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Peptídeos Penetradores de Células/química; Curcumina/química; Curcumina/farmacologia; Curcumina/uso terapêutico; Portadores de Fármacos; Liberação Controlada de Fármacos; Humanos; Neoplasias Pulmonares/metabolismo; Camundongos Nus; Terapia de Alvo Molecular; Nanopartículas/uso terapêutico; Tamanho da Partícula; Poliésteres/química; Polietilenoglicóis/química

Palavras-chave

Cell-penetrating peptide; Cellular uptake; Enzyme-responsive nanoparticles; Matrix metalloproteinase; Tumor extracellular environment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metaloproteinases da Matriz / Nanopartículas / Neoplasias Pulmonares / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: J Nanobiotechnology Ano de publicação: 2018 Tipo de documento: Article

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