Molecular Insights into Muscle Homeostasis, Atrophy and Wasting.
Curr Genomics
; 19(5): 356-369, 2018 Aug.
Article
em En
| MEDLINE
| ID: mdl-30065611
ABSTRACT
Muscle homeostasis is guaranteed by a delicate balance between synthesis and degradation of cell proteins and its alteration leads to muscle wasting and diseases. In this review, we describe the major anabolic pathways that are involved in muscle growth and homeostasis and the proteolytic systems that are over-activated in muscle pathologies. Modulation of these pathways comprises an attractive target for drug intervention.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Curr Genomics
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Itália