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Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.
Saphire, Erica Ollmann; Schendel, Sharon L; Fusco, Marnie L; Gangavarapu, Karthik; Gunn, Bronwyn M; Wec, Anna Z; Halfmann, Peter J; Brannan, Jennifer M; Herbert, Andrew S; Qiu, Xiangguo; Wagh, Kshitij; He, Shihua; Giorgi, Elena E; Theiler, James; Pommert, Kathleen B J; Krause, Tyler B; Turner, Hannah L; Murin, Charles D; Pallesen, Jesper; Davidson, Edgar; Ahmed, Rafi; Aman, M Javad; Bukreyev, Alexander; Burton, Dennis R; Crowe, James E; Davis, Carl W; Georgiou, George; Krammer, Florian; Kyratsous, Christos A; Lai, Jonathan R; Nykiforuk, Cory; Pauly, Michael H; Rijal, Pramila; Takada, Ayato; Townsend, Alain R; Volchkov, Viktor; Walker, Laura M; Wang, Cheng-I; Zeitlin, Larry; Doranz, Benjamin J; Ward, Andrew B; Korber, Bette; Kobinger, Gary P; Andersen, Kristian G; Kawaoka, Yoshihiro; Alter, Galit; Chandran, Kartik; Dye, John M.
Afiliação
  • Saphire EO; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: erica@scripps.edu.
  • Schendel SL; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Fusco ML; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Gangavarapu K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Gunn BM; Ragon Institute, Cambridge, MA 02139, USA.
  • Wec AZ; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Halfmann PJ; Division of Pathobiological Sciences, University of Wisconsin, Madison, WI 53706, USA.
  • Brannan JM; Division of Virology, United States Army Research Institute for Infectious Diseases, Ft. Detrick, MD 21702, USA.
  • Herbert AS; Division of Virology, United States Army Research Institute for Infectious Diseases, Ft. Detrick, MD 21702, USA.
  • Qiu X; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg R3E 3R2, Canada.
  • Wagh K; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
  • He S; National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg R3E 3R2, Canada.
  • Giorgi EE; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
  • Theiler J; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
  • Pommert KBJ; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Krause TB; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Turner HL; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Murin CD; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Pallesen J; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Davidson E; Integral Molecular, Philadelphia, PA 19104, USA.
  • Ahmed R; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Aman MJ; Integrated BioTherapeutics, Rockville, MD 20850, USA.
  • Bukreyev A; Galveston National Laboratory, University of Texas Medical Branch, Galveston, TX 77555, USA.
  • Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Crowe JE; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Davis CW; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Georgiou G; Department of Chemical Engineering, University of Texas at Austin, Austin, TX 78712, USA.
  • Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Kyratsous CA; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.
  • Lai JR; Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Nykiforuk C; Emergent BioSolutions, Winnipeg, Manitoba, R3T 5Y3, Canada.
  • Pauly MH; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
  • Rijal P; Human Immunology Unit, University of Oxford, Oxford OX3 9DS, UK.
  • Takada A; Research Center for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
  • Townsend AR; Human Immunology Unit, University of Oxford, Oxford OX3 9DS, UK.
  • Volchkov V; INSERM CNRS, Université Lyon, Lyon, France.
  • Walker LM; Adimab, LLC. Lebanon, NH 03766, USA.
  • Wang CI; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), Biopolis 138648, Singapore.
  • Zeitlin L; Mapp Biopharmaceutical, San Diego, CA 92121, USA.
  • Doranz BJ; Integral Molecular, Philadelphia, PA 19104, USA.
  • Ward AB; Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Korber B; Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
  • Kobinger GP; Département de Microbiologie-Infectiologie et d'Immunologie, Médecine, Université Laval Quebec, G1V 046 Canada. Electronic address: gary.kobinger@crchudequebec.ulaval.ca.
  • Andersen KG; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: andersen@scripps.edu.
  • Kawaoka Y; Division of Pathobiological Sciences, University of Wisconsin, Madison, WI 53706, USA. Electronic address: kawaokay@svm.vetmed.wisc.edu.
  • Alter G; Ragon Institute, Cambridge, MA 02139, USA. Electronic address: galter@mgh.harvard.edu.
  • Chandran K; Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: kartik.chandran@einstein.yu.edu.
  • Dye JM; Division of Virology, United States Army Research Institute for Infectious Diseases, Ft. Detrick, MD 21702, USA. Electronic address: john.m.dye1.civ@mail.mil.
Cell ; 174(4): 938-952.e13, 2018 08 09.
Article em En | MEDLINE | ID: mdl-30096313

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Doença pelo Vírus Ebola / Ebolavirus / Anticorpos Monoclonais / Epitopos Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Doença pelo Vírus Ebola / Ebolavirus / Anticorpos Monoclonais / Epitopos Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article