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Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy.
Maganti, Harinad B; Jrade, Hani; Cafariello, Christopher; Manias Rothberg, Janet L; Porter, Christopher J; Yockell-Lelièvre, Julien; Battaion, Hannah L; Khan, Safwat T; Howard, Joel P; Li, Yuefeng; Grzybowski, Adrian T; Sabri, Elham; Ruthenburg, Alexander J; Dilworth, F Jeffrey; Perkins, Theodore J; Sabloff, Mitchell; Ito, Caryn Y; Stanford, William L.
Afiliação
  • Maganti HB; The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Jrade H; Ottawa Institute of Systems Biology, Ottawa, Ontario, Canada.
  • Cafariello C; Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.
  • Manias Rothberg JL; The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Porter CJ; Ottawa Institute of Systems Biology, Ottawa, Ontario, Canada.
  • Yockell-Lelièvre J; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.
  • Battaion HL; The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Khan ST; Ottawa Institute of Systems Biology, Ottawa, Ontario, Canada.
  • Howard JP; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.
  • Li Y; The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Grzybowski AT; Ottawa Institute of Systems Biology, Ottawa, Ontario, Canada.
  • Sabri E; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.
  • Ruthenburg AJ; Ottawa Bioinformatics Core Facility, The Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Dilworth FJ; The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Perkins TJ; Ottawa Institute of Systems Biology, Ottawa, Ontario, Canada.
  • Sabloff M; The Sprott Center for Stem Cell Research, Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
  • Ito CY; Ottawa Institute of Systems Biology, Ottawa, Ontario, Canada.
  • Stanford WL; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Cancer Discov ; 8(11): 1376-1389, 2018 11.
Article em En | MEDLINE | ID: mdl-30115703
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Daunorrubicina / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-mdm2 / Complexo Repressor Polycomb 2 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Discov Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Daunorrubicina / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas c-mdm2 / Complexo Repressor Polycomb 2 Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Discov Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá