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S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy.
Chiku, Tomoki; Hayashishita, Motoki; Saito, Taro; Oka, Mikiko; Shinno, Kanako; Ohtake, Yosuke; Shimizu, Sawako; Asada, Akiko; Hisanaga, Shin-Ichi; Iijima, Koichi M; Ando, Kanae.
Afiliação
  • Chiku T; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Hayashishita M; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Saito T; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan; Department of Biological Sciences, Faculty of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Oka M; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Shinno K; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Ohtake Y; Department of Neuroscience, Thomas Jefferson University, Philadelphia, PA, USA.
  • Shimizu S; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Asada A; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan; Department of Biological Sciences, Faculty of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Hisanaga SI; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan; Department of Biological Sciences, Faculty of Science, Tokyo Metropolitan University, Tokyo, Japan.
  • Iijima KM; Department of Alzheimer's Disease Research, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; Department of Experimental Gerontology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi, Japan.
  • Ando K; Department of Biological Sciences, Graduate School of Science, Tokyo Metropolitan University, Tokyo, Japan; Department of Biological Sciences, Faculty of Science, Tokyo Metropolitan University, Tokyo, Japan. Electronic address: k_ando@tmu.ac.jp.
Neurobiol Aging ; 71: 255-264, 2018 11.
Article em En | MEDLINE | ID: mdl-30172839
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas tau / Tauopatias / Proteínas de Drosophila Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Aging Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas tau / Tauopatias / Proteínas de Drosophila Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Aging Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão