Platelet-derived growth factor receptor alpha (PDGFR&#945;) is overexpressed in NK/T-cell lymphoma and mediates cell survival.

Lu, Lisha; Fu, Xiaorui; Li, Zhaoming; Qiu, Yajuan; Li, Weiming; Zhou, Zhiyuan; Xue, Weili; Wang, Yingjun; Jin, Mengyuan; Zhang, Mingzhi

Platelet-derived growth factor receptor alpha (PDGFRα) is overexpressed in NK/T-cell lymphoma and mediates cell survival.

Lu, Lisha; Fu, Xiaorui; Li, Zhaoming; Qiu, Yajuan; Li, Weiming; Zhou, Zhiyuan; Xue, Weili; Wang, Yingjun; Jin, Mengyuan; Zhang, Mingzhi.

Afiliação

Lu L; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Fu X; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Li Z; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Qiu Y; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Li W; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Zhou Z; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Xue W; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Wang Y; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Jin M; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China.
Zhang M; Lymphoma Diagnosis and Treatment Center, Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, PR China. Electronic address: mingzhi_zhang1@163.com.

Biochem Biophys Res Commun ; 504(2): 525-531, 2018 10 02.

Article em En | MEDLINE | ID: mdl-30201265

Assuntos

Linfoma Extranodal de Células T-NK/metabolismo; Receptor alfa de Fator de Crescimento Derivado de Plaquetas/metabolismo; Adulto; Idoso; Animais; Apoptose; Linhagem Celular Tumoral; Proliferação de Células; Sobrevivência Celular; Feminino; Humanos; Mesilato de Imatinib/farmacologia; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Pessoa de Meia-Idade; Transplante de Neoplasias; Prognóstico; Regulação para Cima

Palavras-chave

Imatinib; NK/T-cell lymphoma; PDGFRα

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor alfa de Fator de Crescimento Derivado de Plaquetas / Linfoma Extranodal de Células T-NK Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Biochem Biophys Res Commun Ano de publicação: 2018 Tipo de documento: Article

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