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Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation.
Leng, Lige; Zhuang, Kai; Liu, Zeyue; Huang, Changquan; Gao, Yuehong; Chen, Guimiao; Lin, Hui; Hu, Yu; Wu, Di; Shi, Meng; Xie, Wenting; Sun, Hao; Shao, Zhicheng; Li, Huifang; Zhang, Kunkun; Mo, Wei; Huang, Timothy Y; Xue, Maoqiang; Yuan, Zengqiang; Zhang, Xia; Bu, Guojun; Xu, Huaxi; Xu, Qi; Zhang, Jie.
Afiliação
  • Leng L; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Zhuang K; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Liu Z; State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and Peking Union Medical College, Neuroscience Center, Chinese Academy of Medical Sciences, Beijing 100005, P.R. China.
  • Huang C; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Gao Y; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Chen G; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Lin H; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Hu Y; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Wu D; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Shi M; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Xie W; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Sun H; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Shao Z; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Li H; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Zhang K; School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Mo W; School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Huang TY; Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Xue M; Department of Basic Medical Science, Medical College, Xiamen University, Xiamen, Fujian 361102, P.R. China.
  • Yuan Z; The Brain Science Center, Beijing Institute of Basic Medical Sciences, Beijing 100850, P.R. China.
  • Zhang X; Institute of Mental Health Research at the Royal and Departments of Psychiatry and Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1Z7K4, Canada.
  • Bu G; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China; Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.
  • Xu H; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China; Neuroscience Initiative, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Xu Q; State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and Peking Union Medical College, Neuroscience Center, Chinese Academy of Medical Sciences, Beijing 100005, P.R. China. Electronic address: xuqi@pumc.edu.cn.
  • Zhang J; Fujian Provincial Key Laboratory of Neurodegenerative Disease and Aging Research, Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China. Electronic address: jiezhang@xmu.edu.cn.
Neuron ; 100(3): 551-563.e7, 2018 11 07.
Article em En | MEDLINE | ID: mdl-30220511
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Astrócitos / Proteínas Proto-Oncogênicas / Transtorno Depressivo Maior Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Astrócitos / Proteínas Proto-Oncogênicas / Transtorno Depressivo Maior Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article