Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications.

Okubo, Hirofumi; Kushiyama, Akifumi; Nakatsu, Yusuke; Yamamotoya, Takeshi; Matsunaga, Yasuka; Fujishiro, Midori; Sakoda, Hideyuki; Ohno, Haruya; Yoneda, Masayasu; Asano, Tomoichiro

Okubo, Hirofumi; Kushiyama, Akifumi; Nakatsu, Yusuke; Yamamotoya, Takeshi; Matsunaga, Yasuka; Fujishiro, Midori; Sakoda, Hideyuki; Ohno, Haruya; Yoneda, Masayasu; Asano, Tomoichiro.

Afiliação

Okubo H; Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan. d7276@hiroshima-u.ac.jp.
Kushiyama A; Division of Diabetes and Metabolism, The Institute for Adult Diseases, Asahi Life Foundation, Tokyo 103-0002, Japan. a-kushiyama@asahi-life.or.jp.
Nakatsu Y; Department of Medical Chemistry, Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551, Japan. nakatsu@hiroshima-u.ac.jp.
Yamamotoya T; Department of Medical Chemistry, Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551, Japan. ymmty@hiroshima-u.ac.jp.
Matsunaga Y; Center for Translational Research in Infection & Inflammation, School of Medicine, Tulane University, 6823 St. Charles Avenue, New Orleans, LA 70118, USA. ymatsunaga@tulane.edu.
Fujishiro M; Division of Diabetes and Metabolic Diseases, Nihon University School of Medicine, Tokyo 173-8610, Japan. midori-tky@umin.ac.jp.
Sakoda H; Division of Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan. hsakoda-tky@umin.ac.jp.
Ohno H; Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan. haruyan711@gmail.com.
Yoneda M; Department of Preventive Medicine for Diabetes and Lifestyle-related Diseases, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan. masayone17@hiroshima-u.ac.jp.
Asano T; Department of Medical Chemistry, Division of Molecular Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima 734-8551, Japan. tasano@hiroshima-u.ac.jp.

Int J Mol Sci ; 19(10)2018 Oct 08.

Article em En | MEDLINE | ID: mdl-30297626

Assuntos

Células Enteroendócrinas/metabolismo; Hepatopatia Gordurosa não Alcoólica/etiologia; Animais; Fatores de Crescimento de Fibroblastos/genética; Fatores de Crescimento de Fibroblastos/metabolismo; Peptídeos Semelhantes ao Glucagon/genética; Peptídeos Semelhantes ao Glucagon/metabolismo; Humanos; Peptídeos e Proteínas de Sinalização Intercelular/genética; Peptídeos e Proteínas de Sinalização Intercelular/metabolismo; Neurotensina/genética; Neurotensina/metabolismo; Hepatopatia Gordurosa não Alcoólica/metabolismo; Hepatopatia Gordurosa não Alcoólica/terapia

Palavras-chave

fibroblast growth factor 19; glucagon-like peptide-1; glucagon-like peptide-2; gut-liver axis; neurotensin; non-alcoholic fatty liver disease; non-alcoholic steatohepatitis; resistin like molecule ß

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Enteroendócrinas / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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