Acetylcholine Inhibits Monomeric C-Reactive Protein Induced Inflammation, Endothelial Cell Adhesion, and Platelet Aggregation; A Potential Therapeutic?

Slevin, Mark; Iemma, Rocco S; Zeinolabediny, Yasmin; Liu, Donghui; Ferris, Glenn R; Caprio, Vittorio; Phillips, Nicola; Di Napoli, Mario; Guo, Baoqiang; Zeng, Xianwei; AlBaradie, Raid; Binsaleh, Naif K; McDowell, Garry; Fang, Wen-Hui

Slevin, Mark; Iemma, Rocco S; Zeinolabediny, Yasmin; Liu, Donghui; Ferris, Glenn R; Caprio, Vittorio; Phillips, Nicola; Di Napoli, Mario; Guo, Baoqiang; Zeng, Xianwei; AlBaradie, Raid; Binsaleh, Naif K; McDowell, Garry; Fang, Wen-Hui.

Afiliação

Slevin M; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Iemma RS; Institute of Dementia and Neurolgical Aging, Weifang Medical University, Weifang, China.
Zeinolabediny Y; University of Medicine and Pharmacy, Târgu Mures, Romania.
Liu D; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Ferris GR; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Caprio V; Applied Medical Sciences College, Majmaah University, Al Majma'ah, Saudi Arabia.
Phillips N; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Di Napoli M; Applied Medical Sciences College, Majmaah University, Al Majma'ah, Saudi Arabia.
Guo B; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Zeng X; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
AlBaradie R; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Binsaleh NK; Neurological Service, Ospedale San Camillo de Lellis, Rieti, Italy.
McDowell G; Faculty of Science and Engineering, School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom.
Fang WH; Institute of Dementia and Neurolgical Aging, Weifang Medical University, Weifang, China.

Front Immunol ; 9: 2124, 2018.

Article em En | MEDLINE | ID: mdl-30319609

Assuntos

Acetilcolina/farmacologia; Proteína C-Reativa/imunologia; Células Endoteliais/efeitos dos fármacos; Inflamação/tratamento farmacológico; Agregação Plaquetária/efeitos dos fármacos; Acetilcolina/uso terapêutico; Adesão Celular/efeitos dos fármacos; Adesão Celular/imunologia; Células Endoteliais/fisiologia; Humanos; Inflamação/imunologia; Sistema de Sinalização das MAP Quinases/efeitos dos fármacos; Sistema de Sinalização das MAP Quinases/imunologia; Monócitos/imunologia; Nicotina/farmacologia; Fosforilação/efeitos dos fármacos; Fosforilação/imunologia; Agregação Plaquetária/imunologia; Testes de Função Plaquetária; Tacrina/farmacologia; Células U937

Palavras-chave

CRP; acetylcholine; cell adhesion; inflammation; nicotine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína C-Reativa / Acetilcolina / Agregação Plaquetária / Células Endoteliais / Inflamação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Front Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

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