Pharmacogenetic testing by polymorphic markers G1846A (CYP2D6*4) and C100T (CYP2D6*10) of the CYP2D6 gene in coronary heart disease patients taking ßß-blockers in the Republic of Sakha (YAKUTIA).

Fedorinov, Denis S; Mirzaev, Karin B; Mustafina, Violetta R; Sychev, Dmitriy A; Maximova, Nadezda R; Chertovskikh, Jana V; Popova, Nyurguiana V; Tarabukina, Sardana M; Rudykh, Zoya A

Fedorinov, Denis S; Mirzaev, Karin B; Mustafina, Violetta R; Sychev, Dmitriy A; Maximova, Nadezda R; Chertovskikh, Jana V; Popova, Nyurguiana V; Tarabukina, Sardana M; Rudykh, Zoya A.

Afiliação

Fedorinov DS; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare, Barrikadnaya str., 2/1, Moscow 125993, Russian Federation.
Mirzaev KB; I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Mustafina VR; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare, Moscow, Russian Federation.
Sychev DA; I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation.
Maximova NR; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare, Moscow, Russian Federation.
Chertovskikh JV; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare, Moscow, Russian Federation.
Popova NV; Republican Hospital No. 3, Yakutsk, Russian Federation.
Tarabukina SM; Department of Pharmacy and Pharmacology, Ammosov North-Eastern Federal University, Yakutsk, Russian Federation.
Rudykh ZA; Department of Pharmacy and Pharmacology, Ammosov North-Eastern Federal University, Yakutsk, Russian Federation.

Drug Metab Pers Ther ; 33(4): 195-200, 2018 12 19.

Article em En | MEDLINE | ID: mdl-30325731

Assuntos

Antagonistas Adrenérgicos beta/uso terapêutico; Doença das Coronárias/tratamento farmacológico; Citocromo P-450 CYP2D6/genética; Polimorfismo de Nucleotídeo Único; Antagonistas Adrenérgicos beta/sangue; Idoso; Doença das Coronárias/sangue; Doença das Coronárias/epidemiologia; Doença das Coronárias/genética; Relação Dose-Resposta a Droga; Frequência do Gene; Humanos; Masculino; Pessoa de Meia-Idade; Testes Farmacogenômicos; Federação Russa/epidemiologia

Palavras-chave

CYP2D6*10; CYP2D6*4; Russians; Yakuts; bisoprolol; metoprolol; pharmacogenetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antagonistas Adrenérgicos beta / Citocromo P-450 CYP2D6 / Doença das Coronárias / Polimorfismo de Nucleotídeo Único Tipo de estudo: Risk_factors_studies Limite: Aged / Humans / Male / Middle aged País/Região como assunto: Asia / Europa Idioma: En Revista: Drug Metab Pers Ther Ano de publicação: 2018 Tipo de documento: Article

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