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Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.
McCoull, William; Cheung, Tony; Anderson, Erica; Barton, Peter; Burgess, Jonathan; Byth, Kate; Cao, Qing; Castaldi, M Paola; Chen, Huawei; Chiarparin, Elisabetta; Carbajo, Rodrigo J; Code, Erin; Cowan, Suzanna; Davey, Paul R; Ferguson, Andrew D; Fillery, Shaun; Fuller, Nathan O; Gao, Ning; Hargreaves, David; Howard, Martin R; Hu, Jun; Kawatkar, Aarti; Kemmitt, Paul D; Leo, Elisabetta; Molina, Daniel M; O'Connell, Nichole; Petteruti, Philip; Rasmusson, Timothy; Raubo, Piotr; Rawlins, Philip B; Ricchiuto, Piero; Robb, Graeme R; Schenone, Monica; Waring, Michael J; Zinda, Michael; Fawell, Stephen; Wilson, David M.
Afiliação
  • McCoull W; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Cheung T; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Anderson E; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Barton P; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Burgess J; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Byth K; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Cao Q; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Castaldi MP; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Chen H; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Chiarparin E; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Carbajo RJ; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Code E; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Cowan S; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Davey PR; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Ferguson AD; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Fillery S; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Fuller NO; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Gao N; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Hargreaves D; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Howard MR; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Hu J; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Kawatkar A; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Kemmitt PD; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Leo E; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Molina DM; Pelago Bioscience AB , Banvaktsvägen 20 , 17148 Solna , Sweden.
  • O'Connell N; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Petteruti P; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Rasmusson T; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Raubo P; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Rawlins PB; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Ricchiuto P; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Robb GR; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Schenone M; Broad Institute of Harvard and MIT , 7 Cambridge Center , Cambridge , Massachusetts 02142 , United States.
  • Waring MJ; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
  • Zinda M; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Fawell S; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , Gatehouse Park , Waltham , Massachusetts 02451 , United States.
  • Wilson DM; Oncology and Discovery Sciences, IMED Biotech Unit , AstraZeneca , 310 Cambridge Science Park, Milton Road , Cambridge CB4 0WG , U.K.
ACS Chem Biol ; 13(11): 3131-3141, 2018 11 16.
Article em En | MEDLINE | ID: mdl-30335946
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Talidomida / Quinolonas / Proteínas Proto-Oncogênicas c-bcl-6 / Antineoplásicos Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Talidomida / Quinolonas / Proteínas Proto-Oncogênicas c-bcl-6 / Antineoplásicos Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido