Circulating Plasma Extracellular Vesicles from Septic Mice Induce Inflammation via MicroRNA- and TLR7-Dependent Mechanisms.

Xu, Jinjin; Feng, Yan; Jeyaram, Anjana; Jay, Steven M; Zou, Lin; Chao, Wei

Xu, Jinjin; Feng, Yan; Jeyaram, Anjana; Jay, Steven M; Zou, Lin; Chao, Wei.

Afiliação

Xu J; Translational Research Program, Department of Anesthesiology and Center for Shock Trauma Anesthesiology Research, University of Maryland School of Medicine, Baltimore, MD 21201.
Feng Y; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, People's Republic of China; and.
Jeyaram A; Translational Research Program, Department of Anesthesiology and Center for Shock Trauma Anesthesiology Research, University of Maryland School of Medicine, Baltimore, MD 21201.
Jay SM; Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742.
Zou L; Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742.
Chao W; Translational Research Program, Department of Anesthesiology and Center for Shock Trauma Anesthesiology Research, University of Maryland School of Medicine, Baltimore, MD 21201; wchao@som.umaryland.edu lzou@som.umaryland.edu.

J Immunol ; 201(11): 3392-3400, 2018 12 01.

Article em En | MEDLINE | ID: mdl-30355788

Assuntos

Vesículas Extracelulares/imunologia; Inflamação/imunologia; Macrófagos/imunologia; Glicoproteínas de Membrana/metabolismo; MicroRNAs/genética; Sepse/imunologia; Receptor 7 Toll-Like/metabolismo; Animais; Circulação Sanguínea; Células Cultivadas; Citocinas/metabolismo; Modelos Animais de Doenças; Humanos; Inflamação/genética; Glicoproteínas de Membrana/genética; Camundongos; Fator 88 de Diferenciação Mieloide/genética; Fator 88 de Diferenciação Mieloide/metabolismo; Plasma/metabolismo; Polimixina B/metabolismo; Sepse/genética; Receptor 3 Toll-Like/genética; Receptor 3 Toll-Like/metabolismo; Receptor 7 Toll-Like/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Sepse / MicroRNAs / Receptor 7 Toll-Like / Vesículas Extracelulares / Inflamação / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Immunol Ano de publicação: 2018 Tipo de documento: Article

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