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Clinical Management Protocol for Dental Implants Inserted in Patients with Active Lichen Planus. Part II 4-Year Follow-Up.
Khamis, Aya Khamis; Aboushelib, Moustafa Nabil; Helal, Mohamed Hamdy.
Afiliação
  • Khamis AK; Oral Pathology Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
  • Aboushelib MN; Dental Biomaterials Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
  • Helal MH; Oral Medicine, Diagnosis, Radiology, and Periodontology Department, Faculty of Dentistry, Tanta University, Tanta, Egypt.
J Prosthodont ; 28(5): 519-525, 2019 Jun.
Article em En | MEDLINE | ID: mdl-30357978
PURPOSE: To evaluate marginal bone loss (MBL) of dental implants inserted in active lichen planus patients. MATERIALS AND METHODS: The study included 59 subjects divided into 3 groups depending on their lichen planus diagnosis and administration of a low dose of corticosteroids: 17 healthy individuals, 20 controlled lichen planus patients controlled using low doses of systemic corticosteroids, and 22 noncontrolled lichen planus patients. During 4-year follow-up sessions MBL was evaluated, and biopsies were collected from lichen planus patients and examined. Two-way ANOVA was used to analyze the data (α = 0.05). RESULTS: There was no statistically significant difference in MBL between healthy and controlled patients; however, noncontrolled patients exhibited increased MBL (F = 1309, p < 0.001) which reached 2.53 mm after 4 years. There were significant interactions between state of the disease (F = 1309, p < 0.001), evaluation time (F = 317, p < 0.001), and interaction between state of the disease and observation time (F = 159, p < 0.001). Histopathologic examination of collected biopsies revealed healthy tissue architecture of the controlled patients, while inflammatory cellular infiltration and signs of classical destructive tissue were observed for noncontrolled patients. CONCLUSIONS: Lichen planus patients receiving dental implants should be controlled on a low-dose of corticosteroids to prevent accelerated MBL and to reduce remission of clinical manifestations.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Implantes Dentários / Líquen Plano Bucal / Líquen Plano Tipo de estudo: Guideline / Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Prosthodont Assunto da revista: ODONTOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Egito

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Implantes Dentários / Líquen Plano Bucal / Líquen Plano Tipo de estudo: Guideline / Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: J Prosthodont Assunto da revista: ODONTOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Egito