Asymmetric cell division-dominant neutral drift model for normal intestinal stem cell homeostasis.

Sei, Yoshitatsu; Feng, Jianying; Chow, Carson C; Wank, Stephen A

Sei, Yoshitatsu; Feng, Jianying; Chow, Carson C; Wank, Stephen A.

Afiliação

Sei Y; Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland.
Feng J; Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland.
Chow CC; Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland.
Wank SA; Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , Bethesda, Maryland.

Am J Physiol Gastrointest Liver Physiol ; 316(1): G64-G74, 2019 01 01.

Article em En | MEDLINE | ID: mdl-30359083

Assuntos

Divisão Celular Assimétrica/fisiologia; Homeostase/fisiologia; Intestinos/citologia; Células-Tronco/citologia; Animais; Diferenciação Celular/fisiologia; Linhagem da Célula/fisiologia; Células Cultivadas; Mucosa Intestinal/citologia; Camundongos; Regeneração/fisiologia

Palavras-chave

Moran process; asymmetric cell division; branching process; intestine; lineage tracing; neutral drift; random walk; simulation; spindle orientation; stem cell; stochastic; symmetric cell division

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco / Divisão Celular Assimétrica / Homeostase / Intestinos Limite: Animals Idioma: En Revista: Am J Physiol Gastrointest Liver Physiol Assunto da revista: FISIOLOGIA / GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article

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