Antithrombotic therapy with rivaroxaban in five patients with paroxysmal nocturnal haemoglobinuria and thrombotic events.
Thromb J
; 16: 26, 2018.
Article
em En
| MEDLINE
| ID: mdl-30377413
ABSTRACT
Five patients with paroxysmal nocturnal haemoglobinuria and thrombotic complications under oral antithrombotic treatment with vitamin K antagonist were switched to receive the direct oral anticoagulant rivaroxaban an factor Xa inhibitor. In all five patients haematological and biochemical parameters and adverse events were evaluated for a period of twelve months. Therapy with rivaroxaban was well tolerated in all cases and one patient showed a significant reduction of bleeding and transfusion requirement. All patients obtained a significant reduction in days of hospitalization with a consequent improvement in their quality of life after rivaroxaban treatment.
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Base de dados:
MEDLINE
Idioma:
En
Revista:
Thromb J
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Itália