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Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.
Sievers, Philipp; Stichel, Damian; Hielscher, Thomas; Schrimpf, Daniel; Reinhardt, Annekathrin; Wefers, Annika K; Reuss, David; Jones, David T W; Bewerunge-Hudler, Melanie; Hartmann, Christian; Baumgarten, Peter; Wirsching, Hans-Georg; Winther-Kristensen, Bjarne; Brokinkel, Benjamin; Ketter, Ralf; Idoate Gastearena, Miguel Angel; Lamszus, Katrin; Seiz-Rosenhagen, Marcel; Mawrin, Christian; Harter, Patrick N; Felsberg, Jörg; Hänggi, Daniel; Herold-Mende, Christel; Berghoff, Anna Sophie; Weller, Michael; Pfister, Stefan M; Wick, Wolfgang; Reifenberger, Guido; Preusser, Matthias; von Deimling, Andreas; Sahm, Felix.
Afiliação
  • Sievers P; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.
  • Stichel D; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Hielscher T; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.
  • Schrimpf D; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Reinhardt A; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Wefers AK; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.
  • Reuss D; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Jones DTW; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.
  • Bewerunge-Hudler M; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Hartmann C; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.
  • Baumgarten P; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Wirsching HG; Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.
  • Winther-Kristensen B; Clinical Cooperation Unit Neuropathology, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Brokinkel B; Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.
  • Ketter R; Pediatric Glioma Research Group, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Idoate Gastearena MA; Genomics and Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Lamszus K; Department of Neuropathology, Institute of Pathology, Hannover Medical School (MHH), Hannover, Germany.
  • Seiz-Rosenhagen M; Institute of Neurology (Edinger Institute), University Hospital and Medical Faculty, Goethe University, Frankfurt, Germany.
  • Mawrin C; Department of Neurosurgery, University Hospital and Medical Faculty, Goethe University, Frankfurt, Germany.
  • Harter PN; Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Felsberg J; Department of Pathology, Odense University Hospital, Odense, Denmark.
  • Hänggi D; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
  • Herold-Mende C; Department of Neurosurgery, University Hospital Münster, Münster, Germany.
  • Berghoff AS; Department of Neurosurgery, University Hospital Saarland, Homburg, Saar, Germany.
  • Weller M; Department of Pathology, Clínica Universidad de Navarra, Pamplona, Spain.
  • Pfister SM; Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Wick W; Department of Neurosurgery, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
  • Reifenberger G; Department of Neuropathology, University Magdeburg, Magdeburg, Germany.
  • Preusser M; Institute of Neurology (Edinger Institute), University Hospital and Medical Faculty, Goethe University, Frankfurt, Germany.
  • von Deimling A; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.
  • Sahm F; Institute of Neuropathology, Heinrich Heine University, Düsseldorf, Germany.
Acta Neuropathol ; 136(6): 975-978, 2018 12.
Article em En | MEDLINE | ID: mdl-30382370
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 2 / Aberrações Cromossômicas / Deleção de Sequência / Metilação de DNA / Neoplasias Meníngeas / Meningioma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Acta Neuropathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cromossomos Humanos Par 2 / Aberrações Cromossômicas / Deleção de Sequência / Metilação de DNA / Neoplasias Meníngeas / Meningioma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Acta Neuropathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha