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Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors.
Hyrsova, Lucie; Vanduchova, Alena; Dusek, Jan; Smutny, Tomas; Carazo, Alejandro; Maresova, Veronika; Trejtnar, Frantisek; Barta, Pavel; Anzenbacher, Pavel; Dvorak, Zdenek; Pavek, Petr.
Afiliação
  • Hyrsova L; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic.
  • Vanduchova A; Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Hnevotinska 3, CZ775 15, Olomouc, Czech Republic; Institute of Molecular and Translational Medicine (IMTM), Faculty of Medicine and Dentistry, Palacky University in Olomouc, Hnevotinska 3, CZ775 15, Olomouc
  • Dusek J; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic.
  • Smutny T; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic.
  • Carazo A; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic; Institute of Molecular and Translational Medicine (IMTM), Faculty of Medicine and Dentistry, Palacky University in Olomouc, Hnevotinska 3, CZ775 15, Olomouc
  • Maresova V; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic.
  • Trejtnar F; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic.
  • Barta P; Department of Biophysics and Physical Chemistry, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic.
  • Anzenbacher P; Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Hnevotinska 3, CZ775 15, Olomouc, Czech Republic.
  • Dvorak Z; Department of Cellular Biology and Genetics, Faculty of Sciences, Palacky University in Olomouc, Slechtitelu 27, 783 71, Olomouc, Czech Republic.
  • Pavek P; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, Hradec Kralove, CZ500 05, Czech Republic. Electronic address: petr.pavek@faf.cuni.cz.
Toxicol Lett ; 300: 81-91, 2019 Jan.
Article em En | MEDLINE | ID: mdl-30394306
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estilbenos / Receptores de Esteroides / Interações Alimento-Droga / Inibidores das Enzimas do Citocromo P-450 Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Toxicol Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: República Tcheca
Texto completo
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estilbenos / Receptores de Esteroides / Interações Alimento-Droga / Inibidores das Enzimas do Citocromo P-450 Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Toxicol Lett Ano de publicação: 2019 Tipo de documento: Article País de afiliação: República Tcheca