Direct Rap1/Talin1 interaction regulates platelet and neutrophil integrin activity in mice.

Bromberger, Thomas; Klapproth, Sarah; Rohwedder, Ina; Zhu, Liang; Mittmann, Laura; Reichel, Christoph A; Sperandio, Markus; Qin, Jun; Moser, Markus

Bromberger, Thomas; Klapproth, Sarah; Rohwedder, Ina; Zhu, Liang; Mittmann, Laura; Reichel, Christoph A; Sperandio, Markus; Qin, Jun; Moser, Markus.

Afiliação

Bromberger T; Department Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany.
Klapproth S; Department Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany.
Rohwedder I; Walter Brendel Centre of Experimental Medicine, Klinikum der Universität Munich, Ludwig Maximilians University Munich, Martinsried, Germany.
Zhu L; Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Mittmann L; Walter Brendel Centre of Experimental Medicine, Klinikum der Universität Munich, Ludwig Maximilians University Munich, Martinsried, Germany.
Reichel CA; Department of Otorhinolarynology, Ludwig Maximilians University Munich, Munich, Germany; and.
Sperandio M; Walter Brendel Centre of Experimental Medicine, Klinikum der Universität Munich, Ludwig Maximilians University Munich, Martinsried, Germany.
Qin J; Department of Otorhinolarynology, Ludwig Maximilians University Munich, Munich, Germany; and.
Moser M; Walter Brendel Centre of Experimental Medicine, Klinikum der Universität Munich, Ludwig Maximilians University Munich, Martinsried, Germany.

Blood ; 132(26): 2754-2762, 2018 12 27.

Article em En | MEDLINE | ID: mdl-30442677

Assuntos

Plaquetas/metabolismo; Antígenos CD18/metabolismo; Hemorragia/metabolismo; Neutrófilos/metabolismo; Talina/metabolismo; Proteínas rap1 de Ligação ao GTP/metabolismo; Animais; Plaquetas/patologia; Antígenos CD18/genética; Adesão Celular/genética; Hemorragia/genética; Hemorragia/patologia; Camundongos; Camundongos Mutantes; Neutrófilos/patologia; Fagocitose/genética; Talina/genética; Proteínas rap1 de Ligação ao GTP/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plaquetas / Talina / Antígenos CD18 / Proteínas rap1 de Ligação ao GTP / Hemorragia / Neutrófilos Limite: Animals Idioma: En Revista: Blood Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

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