Sleep-Disordered Breathing and Cerebral Oxygenation During Sleep in Adults With Mild Cognitive Impairment.
Res Gerontol Nurs
; 11(6): 283-292, 2018 11 01.
Article
em En
| MEDLINE
| ID: mdl-30452061
ABSTRACT
The current study examined relationships between laterality in cerebral oxygenation (L-COX), sleep-disordered breathing (SDB), and daytime function in 16 adults with mild cognitive impairment (MCI). All participants underwent two nights of diagnostic polysomnography. Using dual-cerebral oximetry, L-COX was defined by differences ≥4% in right- versus left-sided percent cerebral oxyhemoglobin saturation. Eight patients had SDB. L-COX was found in five patients, but only on nights with SDB. Greater L-COX was associated more severe SDB higher frequency of apneas + hypopneas per hour (r = 0.66, p < 0.01), desaturations per hour (r = 0.73, p < 0.01), and percent time with oxygen saturation <88% (r = 0.65, p < 0.01). Greater laterality, but not severity of SDB, was associated with poorer functional ability (Lawton Instrumental Activities of Daily Living Scale r = -0.83, p = 0.02), lower cognitive function (Mini-Mental State Examination r = -0.76, p = 0.03), and greater daytime sleepiness (Epworth Sleepiness Scale r = 0.85, p < 0.001). L-COX associated with SDB suggests disruptions in cerebral autoregulation and need for aggressive treatment of SDB in individuals with MCI. [Res Gerontol Nurs. 2018; 11(6)282-292.].
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndromes da Apneia do Sono
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Ritmo Circadiano
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Cognição
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Cérebro
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Disfunção Cognitiva
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Hipóxia
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Res Gerontol Nurs
Assunto da revista:
ENFERMAGEM
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GERIATRIA
Ano de publicação:
2018
Tipo de documento:
Article