Srcasm Regulates Tyrosine Kinases in Skin Cancer: Implications for Precision Medicine.
J Investig Dermatol Symp Proc
; 19(2): S103-S105, 2018 Dec.
Article
em En
| MEDLINE
| ID: mdl-30471750
ABSTRACT
Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer in humans, with an incidence of approximately 700,000 cases per year in the United States (Rogers et al., 2010). It is known that cSCC is strongly associated with sun exposure, specifically UVB and UVA, as well as other risk factors, such as human papillomavirus infection, immunodeficiency, and specific medications (Ratushny et al., 2012). However, the precise sequence of biological events leading to tumor development remains unknown. With projected higher incidence of patients with cSCCs in the future, there is a strong need to elucidate the molecular pathways that regulate formation of cSCCs.
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Revista:
J Investig Dermatol Symp Proc
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos