Vesicoureteral Reflux and Renal Scarring in Infants After the First Febrile Urinary Tract Infection.
Med Arch
; 72(4): 272-275, 2018 Oct.
Article
em En
| MEDLINE
| ID: mdl-30514993
ABSTRACT
INTRODUCTION:
The objective of this research was to determine whether vesicoureteral reflux(VUR) was associated with evolution to renal scarring (RS) following a febrile urinary tract infection (UTI) in infants. MATERIALS ANDMETHODS:
Our research included 100 infants, ages up to 1 year with a first febrile UTI. The diagnostic was based on results of laboratory findings, ultrasonography (USG), voiding cystourethrography (VCUG) and initial and control renal scintigraphy (DMSA renal scan) withtechnetium99mTcsuccimer (dimercaptosuccinic acid), to assess the acute pyelonephritis (APN), VUR and RS.RESULTS:
APN was proven with DMSA renal scan in 66 (66%) infants. Twenty-two infants (33.3%) had VUR in-group of patients with APN. On the control DMSA scan, performed 6 months after the first DMSA, the presence of RS was found in 18 (27.27%) infants. In infants with renal scars VUR were discovered in 9 of them (50%).CONCLUSIONS:
The pathogenesis of RS after febrile UTI in young children is multifactorial. Children with VUR have an increased risk for APN and RS. However, VUR is not the only precondition for RS. Creating a renal scarring cannot be imagined without the inflammatory process of the upper urinary system. Therefore, early detection and treatment of febrile UTIs in children and identify children at risk for RS are of primary importance.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pielonefrite
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Infecções Urinárias
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Refluxo Vesicoureteral
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
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Screening_studies
Limite:
Female
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Humans
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Infant
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Male
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Newborn
Idioma:
En
Revista:
Med Arch
Ano de publicação:
2018
Tipo de documento:
Article