Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments.

Fanucchi, Stephanie; Fok, Ezio T; Dalla, Emiliano; Shibayama, Youtaro; Börner, Kathleen; Chang, Erin Y; Stoychev, Stoyan; Imakaev, Maxim; Grimm, Dirk; Wang, Kevin C; Li, Guoliang; Sung, Wing-Kin; Mhlanga, Musa M

Fanucchi, Stephanie; Fok, Ezio T; Dalla, Emiliano; Shibayama, Youtaro; Börner, Kathleen; Chang, Erin Y; Stoychev, Stoyan; Imakaev, Maxim; Grimm, Dirk; Wang, Kevin C; Li, Guoliang; Sung, Wing-Kin; Mhlanga, Musa M.

Afiliação

Fanucchi S; Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Fok ET; BTRI, CSIR Biosciences, Pretoria, South Africa.
Dalla E; Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Shibayama Y; BTRI, CSIR Biosciences, Pretoria, South Africa.
Börner K; Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Chang EY; Department of Medicine, Università degli Studi di Udine, Udine, Italy.
Stoychev S; Gene Expression and Biophysics Group, Division of Chemical, Systems and Synthetic Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Imakaev M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Grimm D; Department of Infectious Diseases/Virology, BioQuant Center, Heidelberg University Hospital, Heidelberg, Germany.
Wang KC; Heidelberg Partner Site, German Center for Infection Research (DZIF), Heidelberg, Germany.
Li G; Department of Dermatology, Stanford University, Stanford, CA, USA.
Sung WK; Biomedical Technologies Group, CSIR Biosciences, Pretoria, South Africa.
Mhlanga MM; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Boston, MA, USA.

Nat Genet ; 51(1): 138-150, 2019 01.

Article em En | MEDLINE | ID: mdl-30531872

Assuntos

Núcleo Celular/genética; RNA Longo não Codificante/genética; Transcrição Gênica/genética; Animais; Linhagem Celular Tumoral; Células Cultivadas; Cromatina/genética; Epigênese Genética/genética; Células HeLa; Histona-Lisina N-Metiltransferase/genética; Histonas/genética; Células Endoteliais da Veia Umbilical Humana; Humanos; Macrófagos/fisiologia; Metilação; Camundongos; Proteína de Leucina Linfoide-Mieloide/genética; Regiões Promotoras Genéticas/genética; Células RAW 264.7; Regulação para Cima/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Núcleo Celular / RNA Longo não Codificante Limite: Animals / Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: África do Sul

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