Differential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins.

Neel, Dana S; Allegakoen, David V; Olivas, Victor; Mayekar, Manasi K; Hemmati, Golzar; Chatterjee, Nilanjana; Blakely, Collin M; McCoach, Caroline E; Rotow, Julia K; Le, Anh; Karachaliou, Niki; Rosell, Rafael; Riess, Jonathan W; Nichols, Robert; Doebele, Robert C; Bivona, Trever G

Neel, Dana S; Allegakoen, David V; Olivas, Victor; Mayekar, Manasi K; Hemmati, Golzar; Chatterjee, Nilanjana; Blakely, Collin M; McCoach, Caroline E; Rotow, Julia K; Le, Anh; Karachaliou, Niki; Rosell, Rafael; Riess, Jonathan W; Nichols, Robert; Doebele, Robert C; Bivona, Trever G.

Afiliação

Neel DS; Department of Medicine, University of California at San Francisco, San Francisco, California.
Allegakoen DV; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Olivas V; Department of Medicine, University of California at San Francisco, San Francisco, California.
Mayekar MK; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Hemmati G; Department of Medicine, University of California at San Francisco, San Francisco, California.
Chatterjee N; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Blakely CM; Department of Medicine, University of California at San Francisco, San Francisco, California.
McCoach CE; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Rotow JK; Department of Medicine, University of California at San Francisco, San Francisco, California.
Le A; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Karachaliou N; Department of Medicine, University of California at San Francisco, San Francisco, California.
Rosell R; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Riess JW; Department of Medicine, University of California at San Francisco, San Francisco, California.
Nichols R; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.
Doebele RC; Department of Medicine, University of California at San Francisco, San Francisco, California.
Bivona TG; Helen Diller Family Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California.

Cancer Res ; 79(3): 546-556, 2019 02 01.

Article em En | MEDLINE | ID: mdl-30538120

Assuntos

Adenocarcinoma de Pulmão/metabolismo; Neoplasias Pulmonares/metabolismo; Proteínas de Fusão Oncogênica/metabolismo; Proteínas Tirosina Quinases/metabolismo; Proteínas Proto-Oncogênicas/metabolismo; Adenocarcinoma de Pulmão/enzimologia; Adenocarcinoma de Pulmão/genética; Adenocarcinoma de Pulmão/patologia; Animais; Antígenos CD/genética; Antígenos CD/metabolismo; Endossomos/metabolismo; Células HEK293; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/patologia; Sistema de Sinalização das MAP Quinases; Camundongos; Camundongos Endogâmicos NOD; Camundongos SCID; Células NIH 3T3; Proteínas de Fusão Oncogênica/genética; Proteínas Tirosina Quinases/genética; Proteínas Proto-Oncogênicas/genética; Sialiltransferases/genética; Sialiltransferases/metabolismo; Proteínas Cotransportadoras de Sódio-Fosfato Tipo IIb/genética; Proteínas Cotransportadoras de Sódio-Fosfato Tipo IIb/metabolismo; Frações Subcelulares/metabolismo; Sindecana-4/genética; Sindecana-4/metabolismo; Proteínas ras/genética; Proteínas ras/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Proteínas de Fusão Oncogênica / Proteínas Proto-Oncogênicas / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2019 Tipo de documento: Article

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