Phytotoxicity reduction of the mercury chloride effect by natural products from Eugenia jambolana Lam.: A new strategy against the toxic metal pollution.
Ecotoxicol Environ Saf
; 170: 461-467, 2019 Apr 15.
Article
em En
| MEDLINE
| ID: mdl-30553924
ABSTRACT
The objective of this work was to evaluate the antioxidant, metal chelating and cytoprotective activity of the Eugenia jambolana Lam. extract, as well as of its flavonoid and tannic fractions, against the action of Mercury Chloride (HgCl2). Flavonoids were quantified and an LC-MS chromatographic analysis was performed to identify secondary metabolites. Fe2+ and Fe3+ chelation tests and antioxidant activity were carried out using the FRAP method. Microbiological tests were performed by microdilution to determine the Minimum Inhibitory Concentration (MIC). From these results the Minimum Bactericidal (MBC) and Minimum Fungicide Concentration (MFC) were evaluated. The allelopathy and cytoprotection assays were performed using eukaryotic and prokaryotic models. The results revealed the presence of phenolic acids and flavonoids in the E. jambolana extract and fractions. The sub-allelopathic concentration (64⯵g/mL) was used and the results demonstrated the E. jambolana potential cytoprotective effect against mercury chloride.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Produtos Biológicos
/
Syzygium
/
Cloreto de Mercúrio
Idioma:
En
Revista:
Ecotoxicol Environ Saf
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Brasil