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PI3Kδ inhibition modulates regulatory and effector T-cell differentiation and function in chronic lymphocytic leukemia.
Hanna, Bola S; Roessner, Philipp M; Scheffold, Annika; Jebaraj, Billy M C; Demerdash, Yasmin; Öztürk, Selcen; Lichter, Peter; Stilgenbauer, Stephan; Seiffert, Martina.
Afiliação
  • Hanna BS; Department of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. b.hanna@dkfz.de.
  • Roessner PM; Department of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Scheffold A; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  • Jebaraj BMC; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  • Demerdash Y; Department of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Öztürk S; Department of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Lichter P; Department of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Stilgenbauer S; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.
  • Seiffert M; Department of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany. m.seiffert@dkfz.de.
Leukemia ; 33(6): 1427-1438, 2019 06.
Article em En | MEDLINE | ID: mdl-30573773

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Purinas / Leucemia Linfocítica Crônica de Células B / Diferenciação Celular / Linfócitos T Reguladores / Linfócitos T CD8-Positivos / Quinazolinonas / Classe I de Fosfatidilinositol 3-Quinases / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Purinas / Leucemia Linfocítica Crônica de Células B / Diferenciação Celular / Linfócitos T Reguladores / Linfócitos T CD8-Positivos / Quinazolinonas / Classe I de Fosfatidilinositol 3-Quinases / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha