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ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension.
Grünig, Ekkehard; Eichstaedt, Christina; Barberà, Joan-Albert; Benjamin, Nicola; Blanco, Isabel; Bossone, Eduardo; Cittadini, Antonio; Coghlan, Gerry; Corris, Paul; D'Alto, Michele; D'Andrea, Antonello; Delcroix, Marion; de Man, Frances; Gaine, Sean; Ghio, Stefano; Gibbs, Simon; Gumbiene, Lina; Howard, Luke S; Johnson, Martin; Jureviciene, Elena; Kiely, David G; Kovacs, Gabor; MacKenzie, Alison; Marra, Alberto M; McCaffrey, Noel; McCaughey, Paul; Naeije, Robert; Olschewski, Horst; Pepke-Zaba, Joanna; Reis, Abílio; Santos, Mário; Saxer, Stéphanie; Tulloh, Robert M; Ulrich, Silvia; Vonk Noordegraaf, Anton; Peacock, Andrew J.
Afiliação
  • Grünig E; Centre for Pulmonary Hypertension, Thoraxclinic at the University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
  • Eichstaedt C; Both authors contributed equally.
  • Barberà JA; Centre for Pulmonary Hypertension, Thoraxclinic at the University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
  • Benjamin N; Both authors contributed equally.
  • Blanco I; Hospital Clinic IDIBAPS, University of Barcelona, Barcelona and Biomedical Research Networking Center on Respiratory Diseases, Madrid, Spain.
  • Bossone E; Centre for Pulmonary Hypertension, Thoraxclinic at the University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
  • Cittadini A; Hospital Clinic IDIBAPS, University of Barcelona, Barcelona and Biomedical Research Networking Center on Respiratory Diseases, Madrid, Spain.
  • Coghlan G; Dept of Cardiac Surgery, University Hospital Salerno, Salerno, Italy.
  • Corris P; Dept of Cardiac Surgery, University Hospital Salerno, Salerno, Italy.
  • D'Alto M; Pulmonary Hypertension Unit, Royal Free Hospital, University College London, London, UK.
  • D'Andrea A; Dept of Respiratory Medicine, Freeman Hospital, University of Newcastle, Newcastle upon Tyne, UK.
  • Delcroix M; Dept of Cardiology, Second University of Naples - Monaldi Hospital, Naples, Italy.
  • de Man F; Dept of Cardiology, Second University of Naples - Monaldi Hospital, Naples, Italy.
  • Gaine S; Dept of Pneumology, University Hospital Leuven, Leuven, Belgium.
  • Ghio S; Dept of Pulmonology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands.
  • Gibbs S; Dept of Respiratory Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.
  • Gumbiene L; Divisione di Cardiologia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy.
  • Howard LS; Faculty of Medicine, Imperial College London, National Heart and Lung Institute, London, UK.
  • Johnson M; Competence Centre of Pulmonary Hypertension, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.
  • Jureviciene E; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
  • Kiely DG; Hammersmith Hospital, Imperial College NHS Trust, London, UK.
  • Kovacs G; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.
  • MacKenzie A; Competence Centre of Pulmonary Hypertension, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania.
  • Marra AM; Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
  • McCaffrey N; Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, UK.
  • McCaughey P; Dept of Internal Medicine, Div. Pulmonology, Medical University of Graz, Graz, Austria.
  • Naeije R; Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
  • Olschewski H; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.
  • Pepke-Zaba J; Dept of Cardiovascular Imaging, IRCCS S.D.N., Naples, Italy.
  • Reis A; Dept of Respiratory Medicine, Mater Misericordiae University Hospital, Dublin, Ireland.
  • Santos M; Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, UK.
  • Saxer S; Dept of Cardiology, University Clinic Brussels - Erasme Hospital, Brussels, Belgium.
  • Tulloh RM; Dept of Internal Medicine, Div. Pulmonology, Medical University of Graz, Graz, Austria.
  • Ulrich S; Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.
  • Vonk Noordegraaf A; Pulmonary Vascular Disease Unit, Papworth Hospital, Cambridge, UK.
  • Peacock AJ; Dept of Internal Medicine, Hospital Geral de Santo António, Porto, Portugal.
Eur Respir J ; 53(2)2019 02.
Article em En | MEDLINE | ID: mdl-30578391
ABSTRACT
Objectives of this European Respiratory Society task force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the task force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiological mechanisms.In studies (784 PH patients in total, including six randomised controlled trials, three controlled trials, 10 prospective cohort studies and four meta-analyses), exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from healthcare institutions, commissioners of healthcare and research funding institutions is greatly needed. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reabilitação / Pneumologia / Terapia por Exercício / Hipertensão Pulmonar Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Eur Respir J Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reabilitação / Pneumologia / Terapia por Exercício / Hipertensão Pulmonar Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Eur Respir J Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha