Alkyne functionalized cellulose fibers: A versatile "clickable" platform for antibacterial materials.
Carbohydr Polym
; 207: 68-78, 2019 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-30600053
ABSTRACT
We report a facile and effective method to fabricate clickable alkyne-functionalized cellulose fibers (ACFs) through in situ chemical oxidation copolymerization of 3-ethynylaniline and aniline under acidic aqueous solution. The effects of process variables on copolymer deposition onto CFs were investigated and suitable preparation conditions were identified. It was found that aniline significantly facilitated the polymerization of 3-ethynylaniline and shortened the preparation time of ACFs from 48 to 6 h. Antibacterial-modified cellulose fibers were prepared by binding ß-cyclodextrin (ß-CD) to cellulose fibers via click chemistry, followed by the inclusion of ciprofloxacin hydrochloride (CipHCl). The loading and releasing behaviors of CipHCl into/from click product (ACFs@Azide-ß-CD) were also revealed. The load amount of CipHCl into ACFs@Azide-ß-CD increased remarkably, and the release of CipHCl from ACFs@Azide-ß-CD was prolonged. The ACFs@Azide-ß-CD loaded with CipHCl exhibited higher and longer-term antibacterial activity against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureu) compared with CFs and ACFs.
Texto completo:
1
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Carbohydr Polym
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
China