Establishment of human embryonic stem cell line Amicqui-2 using poor-quality embryos from Mexican population.
Stem Cell Res
; 34: 101364, 2019 01.
Article
em En
| MEDLINE
| ID: mdl-30611019
Although investigation with human embryonic stem cells (HESC) is not decreasing, the derivation of new lines has been diminished. The preeminence of only a few HESC lines in research is accompanied by lack of universal applicability of results as well as by genetic under-representation. We previously reported the derivation of one line with male karyotype from Mexican population. Here, we derived one HESC line (Amicqui-2) with female karyotype from poor-quality embryos. These line comply the pluripotent requirements (normal karyotype, detection of pluripotency-associated markers, mycoplasma test and teratoma formation) and could be a valuable model for studying diseases specific to under-represented population.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Técnicas de Cultura de Células
/
Embrião de Mamíferos
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Células-Tronco Embrionárias Humanas
Limite:
Animals
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Female
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Humans
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Stem Cell Res
Ano de publicação:
2019
Tipo de documento:
Article