Gaining Weight: Insulin-Eating Islet Macrophages.

Spadaro, Olga; Dixit, Vishwa Deep

Spadaro, Olga; Dixit, Vishwa Deep.

Afiliação

Spadaro O; Department of Comparative Medicine and Yale Center for Research on Aging, New Haven, CT 06520, USA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
Dixit VD; Department of Comparative Medicine and Yale Center for Research on Aging, New Haven, CT 06520, USA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address: vishwa.dixit@yale.edu.

Immunity ; 50(1): 13-15, 2019 01 15.

Article em En | MEDLINE | ID: mdl-30650372

ABSTRACT

ABSTRACT

The role of the immune system in homeostasis of pancreatic ß cells in type 2 diabetes mellitus is poorly characterized. In a recent issue of Cell Metabolism, Ying et al. (2018) report that two subpopulations of macrophages expand during obesity to impair ß cell function.

Assuntos

Diabetes Mellitus Tipo 2; Ilhotas Pancreáticas; Proliferação de Células; Humanos; Inflamação; Insulina; Macrófagos; Obesidade

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Diabetes Mellitus Tipo 2 Limite: Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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