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HDAC3 restrains CD8-lineage genes to maintain a bi-potential state in CD4+CD8+ thymocytes for CD4-lineage commitment.
Philips, Rachael Laura; Lee, Jeong-Heon; Gaonkar, Krutika; Chanana, Pritha; Chung, Ji Young; Romero Arocha, Sinibaldo R; Schwab, Aaron; Ordog, Tamas; Shapiro, Virginia Smith.
Afiliação
  • Philips RL; Department of Immunology, Mayo Clinic, Rochester, United States.
  • Lee JH; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, United States.
  • Gaonkar K; Department of Health Science Research, Division of Biostatistics and Informatics, Mayo Clinic, Rochester, United States.
  • Chanana P; Department of Health Science Research, Division of Biostatistics and Informatics, Mayo Clinic, Rochester, United States.
  • Chung JY; Department of Immunology, Mayo Clinic, Rochester, United States.
  • Romero Arocha SR; Department of Immunology, Mayo Clinic, Rochester, United States.
  • Schwab A; Department of Immunology, Mayo Clinic, Rochester, United States.
  • Ordog T; Epigenomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, United States.
  • Shapiro VS; Department of Immunology, Mayo Clinic, Rochester, United States.
Elife ; 82019 01 18.
Article em En | MEDLINE | ID: mdl-30657451
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos CD4 / Expressão Gênica / Antígenos CD8 / Linhagem da Célula / Timócitos / Histona Desacetilases Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos CD4 / Expressão Gênica / Antígenos CD8 / Linhagem da Célula / Timócitos / Histona Desacetilases Limite: Animals Idioma: En Revista: Elife Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos