HepaDisk - A new quality of life questionnaire for HCV patients.
Dig Liver Dis
; 51(7): 1008-1015, 2019 07.
Article
em En
| MEDLINE
| ID: mdl-30661988
ABSTRACT
BACKGROUND:
Since most patients with hepatitis C virus (HCV) infection now receive treatment irrespective of liver disease severity, special attention to patient quality of life (QoL), including psycho-social aspects, is required. No QoL questionnaire is specific for patients with HCV.AIMS:
To develop and validate a short Italian questionnaire (HepaDisk) assessing the QoL of patients affected by HCV with intuitive graphic results that is understandable by patients and physicians.METHODS:
A questionnaire, drafted by a steering committee, underwent a Delphi survey. A multicenter, observational study was conducted to validate the developed HepaDisk versus other tools (CLDQ-I, SF-36, WPAIHCV), and to evaluate its correlation with disease severity in Italian patients with HCV.RESULTS:
The 10-item questionnaire was validated in 214 patients. HepaDisk showed a high correlation with CLDQ overall score and WPAIHCV activity impairment (Spearman's rank correlation 0.651 and 0.595, respectively) and a lower correlation with SF-36. Strong internal consistency (Cronbach coefficient 0.912), good test-retest reliability (Pearson's correlation coefficient 0.789; 95% CI, 0.714-0.865), and responsiveness to changes among improved patients were demonstrated.CONCLUSION:
HepaDisk is a reliable and user-friendly tool that can monitor disease impact on patient QoL over time, providing a visual representation easily understandable by both patients and physicians.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Qualidade de Vida
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Índice de Gravidade de Doença
/
Inquéritos e Questionários
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Hepatite C
Tipo de estudo:
Clinical_trials
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Observational_studies
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Qualitative_research
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Dig Liver Dis
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Itália