TRPC6 inactivation does not affect loss of renal function in nephrotoxic serum glomerulonephritis in rats, but reduces severity of glomerular lesions.

Kim, Eun Young; Shotorbani, Parisa Yazdizadeh; Dryer, Stuart E

Kim, Eun Young; Shotorbani, Parisa Yazdizadeh; Dryer, Stuart E.

Afiliação

Kim EY; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA.
Shotorbani PY; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA.
Dryer SE; Department of Biology and Biochemistry, University of Houston, Houston, TX, USA.

Biochem Biophys Rep ; 17: 139-150, 2019 Mar.

Article em En | MEDLINE | ID: mdl-30662960

Palavras-chave

BUN, blood urea nitrogen; CKD, chronic kidney disease; Chronic kidney disease; FSGS, focal and segmental glomerulosclerosis; GBM, glomerular basement membrane; Glomerulonephritis; IL-1ß, interleukin 1ß; NLRP3, NOD-like receptor pyrin domain containing-3 protein; NTS, nephrotoxic serum; PAN, puromycin amino nucleoside; PAS, periodic acid-Schiff's stain; Renal fibrosis; SMA, α-smooth muscle actin; TCA, trichloroacetic acid; TNF, tumor necrosis factor; TRPC3, canonical transient receptor potential-3 channel; TRPC5, canonical transient receptor potential-5 channel; TRPC6; TRPC6, canonical transient receptor potential-6 channel; UUO, unilateral ureteral obstruction; suPAR, soluble urokinase receptor

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Biochem Biophys Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google